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|Título:||Evaluation of clinical parameters in people living with HIV undergoing pharmacotherapeutic monitoring : viral load, CD4 + T lymphocytes and adherence to antiretrovirals|
|Autor(es):||Reis, Henry Pablo L. C.|
Cândido, Darlan da S .
Loureiro, Catarine V.
Carlos, Juliana de O.
Araújo, Ana Maria S. de
Batista, Maria Jacqueline
Fonteles, Marta Maria de F.
|Data do documento:||Mar-2016|
|Editor:||African Journa l of Pharmacy and Pharmacology|
|Citação:||REIS, H. P. L. C. ; CÂNDIDO, D. S . ; LOUREIRO, C. V. ; CARLOS, J. O. ; ARAÚJO, A. M. S. ; BATISTA, M. J. ; FONTELES, M. M. F. (2016)|
|Abstract:||The aim of this study was to evaluate the clinical indicators ( viral load - VL, CD4 lymphocytes and adherence) of HIV + patients, at the beginning of treatm ent with antiretrovirals (ARV) , during pharmacotherapeutic monitoring (PTM) in a specialized center in Fortaleza, Ceará. The longitudinal study, according to the Dáder method , was used for patients with HIV (n = 100) from 2008 to 2012, beginning at the tim e of dispensation of the antiretroviral therapy. The data were analyzed using SPSS ® . To evaluate the VL and CD4 levels, the Wilcoxon's test was carried out and the patients were used as temporal control s for themselves regarding the outcomes assessed at th e beginning and end of the PTM. Adherence was determined by self - report and pharmacy dispensing records ( PD R) of anti r etrovirals. There was a mean reduction of 89.45% (SD = 0.28986) in total VL (p < 0.001). For CD4+ lymphocytes, a mean increase of 124.14% (SD = 1.31756) was detected (p <0.001) during the PTM. Most treated patients showed high rates of adherence by self - report (95.0%, n = 100) and (76. 0%) P D R methods. The findings of the present work demonstrate d the potential benefits of PTM on treatment ad herence, which may have be en decisive for the success ful improvement of the assessed clinical indicators. The inclusion of PTM for people living with HIV/AIDS ( PLHIV/AIDS ) in clinical services should be encouraged at the level of secondary health care.|
|Descrição:||REIS, Henry Pablo L. C. et al. Evaluation of clinical parameters in people living with HIV undergoing pharmacotherapeutic monitoring : viral load, CD4+ T lymphocytes and adherence to antiretrovirals. African Journal of Pharmacy and Pharmacology, v. 10, p. 236-243, mar. 2016.|
|ISSN:||1996 - 0816|
|Aparece nas coleções:||DFIFA - Artigos publicados em revista científica|
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