Use este identificador para citar ou linkar para este item: http://www.repositorio.ufc.br/handle/riufc/20467
Título: Dino fl agellate-related amphidinolides from the brazilian octocoral stragulum bicolor
Autor(es): Nuzzo, Genoveffa
Gomes, Bruno A.
Luongo, Elvira
Torres, Maria C. M.
Santos, Evelyne A.
Cutignano, Adele
Pessoa, Otília D. L.
Costa-Lotufo, Leticia V.
Fontana, Angelo
Palavras-chave: Cnidários
Cnidaria
Data do documento: Jul-2016
Editor: Journal of Natural Products
Citação: NUZZO, G. ; GOMES, B. A. ; LUONGO, E. ; TORRES, M. C. M. ; SANTOS, E. A. ; CUTIGNANO, A. ; PESSOA, O. D. L. ; COSTA-LOTUFO, L. V. ; FONTANA, A. (2016)
Abstract: ABSTRACT: Benthic cnidarians are colonial marine animals that host a rich population of associated and symbiotic microorganisms. In a recent paper we described for the first time the isolation of amphidinolide P (1) from the Brazilian octocoral Stragulum bicolor. Amphidinolides and similar compounds had been previously reported only from dinoflagellates of the genus Amphidinium; thus the presence of 1 in the invertebrate opens intriguing questions on the role and occurrence of these molecules in marine ecosystems. Here we report the identification of four further amphidinolides from the same soft coral, including the known amphidinolide T1 (2) and the new analogues here named amphidinolides C4 (3), B8 (4), and B9 (5). The chemical structures have been elucidated mainly by extensive study of spectroscopic data. Cytotoxic activities of 3 and 4 were evaluated against the colon adenocarcinoma cell line HCT-116
Descrição: NUZZO, Genoveffa et al. Dinoflagellate-Related Amphidinolides from the Brazilian Octocoral Stragulum bicolor. Journal of Natural Products, Cincinnati, v. 79, p. 1881-1885, jul. 2016.
URI: http://www.repositorio.ufc.br/handle/riufc/20467
ISSN: 0163-3864
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