Please use this identifier to cite or link to this item: http://www.repositorio.ufc.br/handle/riufc/35290
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dc.contributor.authorA. Filho, A. C. V.-
dc.contributor.authorRodrigues, P. A. S.-
dc.contributor.authorBenjamin, S. R.-
dc.contributor.authorPaim, R. T. T.-
dc.contributor.authorHolanda, M. O.-
dc.contributor.authorSilva, J. Y. G.-
dc.contributor.authorMilo, T. S.-
dc.contributor.authorVieira, I. G. P.-
dc.contributor.authorQueiroz, M. G. R.-
dc.contributor.authorGuedes, M. I. F.-
dc.date.accessioned2018-08-30T15:14:41Z-
dc.date.available2018-08-30T15:14:41Z-
dc.date.issued2017-12-
dc.identifier.citationA. FILHO, A. C. V. et al. Hypolipidemic activity of P-methoxycinnamic diester (PCO-C) isolated from Copernicia prunífera against Triton WR-1339 and hyperlipidemic diet in mice. nvironmental Toxicology and Pharmacology, Amsterdam, v. 56, p. 198-203, dec. 2017.pt_BR
dc.identifier.issn1382-6689-
dc.identifier.issn1872-7077 (Online)-
dc.identifier.urihttp://www.repositorio.ufc.br/handle/riufc/35290-
dc.description.abstractCarnauba wax is extracted from the leaves of the Copernicia prunífera and contains approximately 80% of esters in its composition. The purpose of the present study was evaluate the hypolipidemic effect of p-methoxycinnamic diesters (PCO-C) extracted from Copernicia prunífera in a model of acute and chronic dyslipidemia in mice. The levels of total cholesterol and triglycerides were significantly reduced plasma levels in PCO-C at the dose of 100 mg/kg in a model of acute and chronic dyslipidemia. Histological studies showed that PCO-C has no hepatotoxic effect and reduces hepatic steatosis in animals that consumed hyperlipidemic ration. Thus, it was concluded that PCO-C isolated from Copernicia Prunifera was effective in reducing total cholesterol and triglyceride levels in both dyslipidemia induction models. The finding indicates that PCO-C might be beneficial in treatment of hyperlipidemia and atherosclerosis.pt_BR
dc.language.isoenpt_BR
dc.publisherEnvironmental Toxicology and Pharmacologypt_BR
dc.subjectDislipidemiaspt_BR
dc.subjectDyslipidemiaspt_BR
dc.titleHypolipidemic activity of P-methoxycinnamic diester (PCO-C) isolated from Copernicia prunífera against Triton WR-1339 and hyperlipidemic diet in micept_BR
dc.typeArticlept_BR
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