Please use this identifier to cite or link to this item: http://www.repositorio.ufc.br/handle/riufc/49653
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dc.contributor.authorMartins, Ana Caroline Vieira-
dc.contributor.authorLima Neto, Pedro de-
dc.contributor.authorBarroso Neto, Ito Liberato-
dc.contributor.authorCavada, Benildo Sousa-
dc.contributor.authorFreire, Valder Nogueira-
dc.contributor.authorCaetano, Ewerton Wagner Santos-
dc.date.accessioned2020-01-24T17:44:24Z-
dc.date.available2020-01-24T17:44:24Z-
dc.date.issued2013-
dc.identifier.citationMARTINS, Ana Caroline Vieira; LIMA-NETO, Pedro de; NETO, Ito Liberato Barroso; CAVADA, Benildo Sousa; FREIRE, Valder Nogueira; CAETANO, Ewerton Wagner Santos. An ab initio explanation of the activation and antagonism strength of an AMPA-sensitive glutamate receptor. RSC Advances, v. 3, n. 35, p. 1-5, 2013.pt_BR
dc.identifier.issn2046-2069-
dc.identifier.urihttp://www.repositorio.ufc.br/handle/riufc/49653-
dc.description.abstractWe report quantum biochemistry calculations focusing on the binding pocket of the glutamate receptor co-crystallized with agonists (full and partial) and a antagonist. The calculated electronic binding energy follows the order AMPA . glutamate. kainate . DNQX, which explains published experimental data on GluR2 activation and antagonism strength.pt_BR
dc.language.isoenpt_BR
dc.publisherRSC Advancespt_BR
dc.subjectCentral nervous systempt_BR
dc.subjectAmino acidspt_BR
dc.subjectElectrophysiologicalpt_BR
dc.titleAn ab initio explanation of the activation and antagonism strength of an AMPA-sensitive glutamate receptorpt_BR
dc.typeArtigo de Periódicopt_BR
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