Efeitos da L-glutamina nas respostas metabólicas e hemodinâmicas em indivíduos sedentários submetidos ao esforço físico

Abstract

The aim of this study was to evaluate the hemodynamic and metabolic responses of L-Glutamine in sedentary subjected to physical exertion. The sample consisted of 11 sedentary volunteers (05 men and 06 women between 30 - 45 years). We conducted a clinical study, crossover, randomized, double-blind. The protocol was divided into two stages. The protocols used participant (0.5 g / kg) of L-glutamine or calcium caseinate added to a milk drink Nescau Light (200ml) for seven consecutive days, with an interval of one week of completion of a protocol and early other. The volunteers were evaluated for cardiopulmonary and metabolic response during cardiopulmonary exercise testing on a treadmill. Were determined in each individual oxygen consumption (VO2 Max), respiratory quotient (RQ), the workload performed, heart rate (HR), systolic and diastolic blood pressure (SBP / DBP) in phases: pre - effort, the anaerobic threshold, maximal effort and during the recovery effort. Were also evaluated serum concentrations of glucose and lactate in four stages: fast (at least 8 hours), immediately before the effort at the end of exercise and 30 minutes after exercise. The prior offer of L-glutamine (0.5 g / kg in sedentary individuals, orally for seven days did not cause hemodynamic changes during physical exertion. On the other hand modified the metabolic response by reducing the lactacemia before the physical activity (3, 68 ± 0.8 versus 2.2 ± 0.9, p = 0.01) in the presence of maximal (12.4 ± 5.1 versus 10.3 ± 3.2, p = 0.04), and at the end of the exercise stress test (6.9 ± 3.6 versus 5.02 ± 1.77, p = 0.01). L-glutamine in nutraceutical doses is recommended for use to practitioners of physical activity and not hemodynamic features.