Use este identificador para citar ou linkar para este item: http://www.repositorio.ufc.br/handle/riufc/17740
Título: Primary cardiac lymphoblastic B‑cell lymphoma : should we treat more intensively?
Autor(es): Ferreira Filho, Luiz Ivando Pires
Ribeiro Junior, Howard Lopes
Pinheiro Júnior, Edílson Diógenes
Pinheiro, Ronald Feitosa
Palavras-chave: Linfócitos B
Leucemia-Linfoma Linfoblástico de Células Precursoras
Data do documento: 2015
Editor: Journal of Cancer Research and Therapeutics
Citação: FERREIRA FILHO, L. I. P. ; RIBEIRO JUNIOR, H. L. ; PINHEIRO JÚNIOR, E. D. ; PINHEIRO, R. F. (2015)
Abstract: Primary cardiac lymphoma (PCL) is a rare neoplasm, the majority of cases of which are non‑Hodgkin’s, diffuse large B‑cell (DLBCL). We report the first case of an adult with PCL B‑cell lymphoblastic lymphoma whose disease evolution was grim. A 52‑year‑old male reported dyspnea and facial swelling lasting for 4 months and upon a physical examination he presented bradycardia, jugular venous engorgement, and hypophonesis of cardiac sounds. An electrocardiography (Echo) revealed a right atrial mass and nodules at the pericardium. The patient was treated with R‑Hyper‑CVAD (rituximab plus cyclophosphamide, vincristine, doxorubicin, and dexamethasone) and presented very short remission. At this time, we used R‑ICE (rituximab plus ifosfamide, carboplatin, and etoposide) chemotherapy and the patient underwent complete remission after two courses and received autologous bone marrow transplantation (auto‑BMT). After 75 days of follow‑up, the patient reported dyspnea and a new Echo showed a recurrence of the disease. The patient died due to cardiac failure. PCL is a rare disease with an unfavorable prognosis and a prompt diagnosis and treatment are fundamental to survival. We believe that more intensive therapies, such as auto‑BMT, should be considered as a first treatment option.
Descrição: FERREIRA FILHO, Luiz Ivando Pires ; RIBEIRO JUNIOR, Howard Lopes ; PINHEIRO JUNIOR, Edílson Diógenes ; PINHEIRO, Ronald Feitosa. Primary cardiac lymphoblastic B‑cell lymphoma : Should we treat more intensively?. Journal of Cancer Research and Therapeutics, v. 11, p. 1034-1037, 2015.
URI: http://www.repositorio.ufc.br/handle/riufc/17740
ISSN: 0973-1482
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