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Title in Portuguese: Evaluation of the antifungal effect vitis vinifera extracton Candida albicans
Author: Gadelha, Leandro Maciel Uchoa
Valada, Lídia Audrey Rocha
Fiallos, Nicole de Mello
Peralt, Sônia Luque
Mendonça, Keniesd Sampaio
Lotif, Mara Assef Leitão
Bezerra, Gilvan Lima
Aguia, Márcio Glauber Lopes de
Diógenes, Érika Sabóia Guerra
Rodrigues Neto, Edilson Martins
Asevedo, George Otávio
Fiallo, Ana Cristina de Mello
Keywords: Extrato de Sementes de Uva
Grape Seed Extract
Candida albicans
Prótese Dentária
Dental Prosthesis
Issue Date: Mar-2018
Publisher: Journal of Young Pharmaciation
Citation: GADELHA, Leandro Maciel Uchoa et al. Evaluation of the antifungal effect Vitis vinifera extract on Candida albicans. Journal of Young Pharmacists, v. 10, n. 2, p. 164-168, mar. 2018.
Abstract: Objective: This research analyzed in vitro the antifungal activity of the solution composed by grapes seed extract Vitis vinifera (Doctor’s A-Z®) against Candida albicans (ATCC 20231) species aiming to determine the minimum inhibitory concentration (MIC) and minimum fungicide concentration (MFC). Methods: To that, were used micro dilution boards of 96 wells where the strain of Candida. Was tested the diluted solutions in distilled water on the concentrations 0.20 g/mL, 0.30 g/mL and 0.40 g/mL. As growing control were used growing fungous, to test the viability of the strains. As positive control, was used nystatin (commercial suspension 100,000 UI/mL) and as sterility control of growing way. The tests were conducted in triplicate and the data obtained were analyzed through the exam Kruskal-Wallis, with significance level of 95% (p<0.05). Results: The results indicated that all the samples were sensible to the analyzed extract and the CIM was obtained with the solution of 0.30 g/mL (30%). However, wasn’t observed a fungicid effect (MFC) on the tested concentrations. Conclusion: We conclude that the grapes seed extract can be an alternative against the gender Candida, however are necessary larger studies to prove their ant fungous action.
metadata.dc.type: Artigo de Periódico
ISSN: 0975-1483
Online - 0975-1505
Appears in Collections:DFAR - Artigos publicados em revistas científicas

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