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Title in Portuguese: Association between endoscopic findings and histopathological confirmation in patients with suspicion of eosinophilic esophagitis
Author: Barbosa, João Paulo Cândido
Tavares, Paulo Roberto Veras
Aguiar, Priscilla Mariana Freitas
Franco, Luciano Monteiro
Nobre-e-Souza, Miguel Ângelo
Souza, Marcellus Henrique Loiola Ponte
Keywords: Esofagite Eosinofílica
Eosinophilic Esophagitis
Doenças do Esôfago
Esophageal Diseases
Issue Date: Apr-2019
Publisher: Arquivos de Gastroenterologia
Citation: BARBOSA, João Paulo Cândido et al. Association between endoscopic findings and histopathological confirmation in patients with suspicion of eosinophilic esophagitis. Arq. Gastroenterol., São Paulo, v. 56, n. 2, p. 151-154, apr./jun. 2019.
Abstract: Background – The diagnosis of eosinophilic esophagitis (EoE) is performed by the detection of 15 or more eosinophils per field in an esophageal biopsy sample, but the endoscopic findings alone are not validated for a diagnosis of the disease. Objective – To evaluate the association between the endoscopic findings and histopathological diagnosis in patients with suspected EoE in endoscopy. Methods – A retrospective study of 24 patients with suspicion of EoE during endoscopy was held. The information was collected from databases of Endoscopy and Pathology services of the Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, from March 2012 to April 2018. The patients were divided into a group with positive biopsy (>15 Eosinophils/field, N=8) and a group with negative biopsy (<15 Eosinophils/field, N=16), and the endoscopic findings were compared between the two groups. Results – From a total of 24 patients, 79.1% had longitudinal grooves, 20.8% white exudates, 33.3% mucosal pallor or loss of vascularity and 45.8% had more than one endoscopic finding. There was a significant difference (P<0.05) in the evaluation of the finding of mucosal pallor or decreased vasculature alone among the groups. The positive predictive value and negative predictive value of the presence of more than one endoscopic findings for the diagnosis of EoE was 54% and 84%, respectively. Conclusion – There was a low association between the presence of endoscopic findings and histopathological confirmation of the disease, which indicates that endoscopic findings alone are not reliable for the diagnosis of EoE.
metadata.dc.type: Artigo de Periódico
ISSN: Print 0004-280
On-line 1678-4219
Appears in Collections:DFIFA - Artigos publicados em revista científica

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