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Title in Portuguese: Drug interactions in Brazilian type 2 diabetes patients
Author: Araújo, Márcio Flávio Moura de
Alves, Priscila de Jesus dos Santos
Veras, Vivian Saraiva
Araújo, Thiago Moura de
Zanetti, Maria Lúcia
Damasceno, Marta Maria Coelho
Keywords: Anti-Hipertensivos
Issue Date: Aug-2013
Publisher: International Journal of Nursing Practice
Citation: ARAÚJO, M. F. M. Drug interactions in Brazilian type 2 diabetes patients. International Journal of Nursing Practice, v. 19, n. 4, p. 423-430, ago. 2013.
Abstract: The aim of this paper is to identify the prevalence of the most frequent drug interactions in patients using oral antidiabéticos and their association with capillary glucose and medication adherence. In total, 579 type 2 diabetes mellitus patients from 12 health institutions in Fortaleza, Brazil were interviewed in 2009. A form was applied, including questions on medication use, comorbidities, lifestyle, body mass index and random capillary glucose. Results revealed that 26.7% used five or more different drugs simultaneously and daily. Statistically significant drug interactions occurred between antidiabéticos and diuretics, angiotensin-converting enzyme inhibitors, anti-lipidaemics and corticoids. No significant association was found between polypharmacy, medication adherence and glucose. It is important for nurses, in consensus with other health professionals, to consider the possibility of other drugs that mean less risk for diabetes patients’ glucose control or of increased antidiabetics doses.
ISSN: 1440-172X Online
Appears in Collections:DENF - Artigos publicados em revistas científicas

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