Please use this identifier to cite or link to this item: http://www.repositorio.ufc.br/handle/riufc/9124
Title in Portuguese: Antiperoxidative properties of oil mixes of high ratio Omega-9, Omega-6 and low ratio Omega-6, Omega-3 after molar extraction in rats
Author: Melo, Radamés Bezerra
Guimarães, Sérgio Botelho
Silva, Paulo Goberlânio de Barros
Oriá, Reinaldo Barreto
Melo, José Ulisses de Souza
Vasconcelos, Paulo Roberto Leitão
Keywords: Ácidos Graxos Ômega-3
Ácidos Graxos Ômega-6
Ratos
Issue Date: Jun-2014
Publisher: Acta Cirúrgica Brasileira
Citation: MELO, R. B. et al. Antiperoxidative properties of oil mixes of high ratio Omega-9, Omega-6 and low ratio Omega-6, Omega-3 after molar extraction in rats. Acta Cirúrgica Brasileira, São Paulo, v. 29, n. 6, p. 371-75, jun. 2014.
Abstract: PURPOSE: To evaluate the antioxidant and antiperoxidative effects of oil mixes of high ratio Omega-9:Omega-6 and low ratio Omega-6:Omega-3 in the third day after tooth extraction in rats.METHODS: Thirty-two male Wistar rats (270-310g) were randomly distributed in two groups: Control (n=24) and Test (n=8). Control group was divided into three subgroups (n=8): G1: Sham-Saline; G2: Saline; G3: Isolipid. G1 and G2 animals received NaCl 0.9% while G3 rats were treated with an isolipid mixture (alpha-linolenic acid – ALA) containing -6/-3 oils (8:1 ratio) and-9/-6 (0.4:1 ratio). Test group animals (G4) received oily mixtures (alpha-linolenic acid – ALA, docosahexaenoic acid – DHA, eicosapentaenoic acid – EPA) of -6/-3 (1.4:1 ratio) and -9/-6 (3.4:1 ratio). Saline and oils were administered by gavage during four days before and three days after first mandibular molar extraction. Following, samples (arterial blood and alveolar mucosa) were collected for glutathione (GSH) and thiobarbituric acid reactive substances (TBARS) assays. RESULTS: Oil mixes induced a significant decrease in GSH and TBARS tissue and plasma concentrations in the third day post-surgery.CONCLUSION: Gavage administration of oil mixes of high ratio Omega-9:Omega-6 and low ratio Omega-6:Omega-3 after molar extraction in rats induces a significant decrease in lipid peroxidation.
URI: http://www.repositorio.ufc.br/handle/riufc/9124
metadata.dc.type: Artigo
ISSN: 0102-8650
Appears in Collections:DCOD - Artigos publicados em revistas científicas

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